vinyl chloride toxicity

The target organs for VC now clearly in … Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1997. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1990. 21, No. Agency for Toxic Substances and Disease Registry (ATSDR). Vinyl chloride | H2C=CHCl or (C2H3Cl)n or C2H3Cl | CID 6338 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. The vinyl industry lobbies to keep consumers believing that vinyl is safe in spite of mounting evidence to the contrary. What is vinyl chloride? For more than 30 years, leading health, environmental justice, and health-impacted organizations across the country and world have been campaigning to phase out this poison plastic. Vinyl chloride is a colorless gas with a mildly sweet smell that easily burns.It is not a naturally-occurring substance and must be manufactured industrially for its commercial purposes. Longer exposures have been associated with headache, dizziness, euphoria, ataxia, and narcosis. Case Studies in Environmental Medicine. Combustion is, of course, an oxidation reaction. (1960). ... Vinyl chloride . The residual vinyl chloride content in polymers in contact with food should be limited to:-5 ppb in vinyl chloride mono- or co-polymer films and coatings, and plasticised polyvinyl chloride (PVC) bottles;-10 ppb in rigid PVC;-50 ppb in water-pipes and vinyl chloride-vinylidene chloride copolymer films. Toxicological Profile for Vinyl Chloride (Update). The current Proposition 65 list is dated December 18, 2020. Exposure of mice to 1000 ppm of vinyl chloride (VC), 6 hr/day, 5 days/week, caused some acute deaths with toxic hepatitis and marked tubular necrosis of the renal cortex. CAS Number 75-01-4 Synonym(s) Vinyl flooring can be an enormous source of off-gassing in your home. [ifediba.com] The gas can cause dizziness, drowsiness, and headache when inhaled. Toxicological Profile for Vinyl Chloride (Update). Vinyl chloride can be formed when other substances such as trichloroethane and trichloroethylene are broken down. Learn more about it. Discovered in 1835, it is used as an intermediate in the production of polyvinyl chloride (PVC), which is molded into PVC piping and bottles. No other plastic contains or releases as many dangerous chemicals. Polyvinyl chloride, also known as PVC or vinyl, is a synthetic resin produced from the polymerization of vinyl chloride.It is an odorless and solid plastic and can come in the form of white powder or pellets. Meetings, Hearings and Workshops. [Note: Shipped as a liquefied compressed gas.] Acute Inhalation Toxicity of Vinyl Chloride to Laboratory Animals. Vinyl chloride has little acute toxicity, and air levels over 8000 ppm may be tolerated for 5 minutes without the development of symptoms. Vinyl Chloride. It is used in the plastics industry, often to produce PVC (polyvinyl chloride) and does not occur naturally in the environment. Agency for Toxic Substances and Disease Registry (ATSDR). Vinyl chloride monomer (VCM) is a colorless, gaseous, sweet-smelling organochloride primarily used in the production of polyvinyl chloride (PVC) with additional historical usage before the 1970s as an aerosol propellant and refrigerant. Smaller amounts of vinyl chloride are used in furniture and automobile upholstery, wall coverings, housewares, and automotive parts. It does not occur naturally and must be produced industrially for its commercial uses. Studies of workers in polyvinyl chloride polymerization of certain plastic and rubber factories revealed that numerous workers had been diagnosed with liver angiosarcoma. Starting the sixth month, mice exposed to 1000, 250, or 50 ppm of VC became lethargic, lost weight quickly, and died. Keith G. Tolman, Anthony S. Dalpiaz, in Drug-Induced Liver Disease (Third Edition), 2013. Polyvinyl chloride is more often referred to by its less-technical names, PVC and vinyl. Vinyl releases toxins during manufacture and disposal, and it’s usually softened with phthalates, which are toxic. Although the industries that use this chemical have known about the harmful effects of vinyl chloride for decades, it has only recently been identified as a known carcinogen. [4] PVC—polyvinyl chloride, or vinyl—is found in a range of products, from children's toys to building materials to food packaging. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1997. Polyvinyl chloride (colloquial: polyvinyl, vinyl; abbreviated: PVC) is the world's third-most widely produced synthetic plastic polymer (after polyethylene and polypropylene).About 40 million tons of PVC are produced each year. Small quantities of vinyl chloride can be released to food since it is used to make many food wrappings and containers. 7.3 Carcinogenicity According to IARC, vinyl chloride is carcinogenic to humans (Group 1). Next to polyethylene, it is the most widely used plastic in the world. Only a few … Starting the sixth month, mice exposed to 1000, 250, or 50 ppm of VC became lethargic, lost weight quickly, and died. The PVC will create a large number of toxic chemicals like dioxins and phthalates that are released into the air and can produce toxic fumes into the environment. [1] [2][3] VCM is now classified as an International Agency for Research on Cancer (IARC) Group 1 carcinogen. Chloroethene, Chloroethylene, Ethylene monochloride, Monochloroethene, Monochloroethylene, VC, VCM, Vinyl chloride monomer (VCM) Colorless gas or liquid (below 7°F) with a pleasant odor at high concentrations. Toxic substances list: vinyl chloride Vinyl chloride (VC) is a flammable and explosive colourless gas with a sweet odour. (2) Uses Most of the vinyl chloride produced in the United States is used to make polyvinyl chloride (PVC), a material used to manufacture a variety of plastic and vinyl products including pipes, wire and cable coatings, and packaging materials. These releases … Therefore, based on information available today, vinyl cannot be non-toxic… The following reference says about vinyl chloride: "On combustion, it degrades to hydrogen chloride, carbon dioxide and traces of phosgene.". Toxicity Data for: Vinyl Chloride Monomer*LD50 (rat, inhalation): 18 pph /15M Vinyl Chloride Monomer* is an OSHA cancer suspect agent, ACGIH confirmed human carcinogen, and NTP and IARC human carcinogen. (4) • The odor threshold for vinyl chloride ranges from 260 ppm to 4,000 ppm. The Proposition 65 List. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1990. PVC – the Poison Plastic. Vinyl Chloride Toxicity. In 1974, vinyl chloride (VC) was first reported in the open scientific literature to induce angiosarcoma of the liver both in humans and in animals. (4) • The chemical formula for vinyl chloride is C 2 H 3 Cl and the molecular weight is 62.5 g/mol. An emerging toxic plastic of concern, polyvinyl chloride (PVC or vinyl), is used widespread in schools across the nation. Toxic Exposure Injury Attorneys - Serving Clients Nationwide. Keep away from open flames/hot surfaces. The major industrial preparation of vinyl chloride begins with ethylene and has two Exposure of mice to 1000 ppm of vinyl chloride (VC), 6 hr/day, 5 days/week, caused some acute deaths with toxic hepatitis and marked tubular necrosis of the renal cortex. Vinyl chloride is a highly dangerous chemical used to make numerous plastic materials. One reason why PVC is so toxic is that it is often mixed with softening chemicals called plasticizers, the most well known variety being phalates. for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to vinyl chloride. Upcoming and past meetings, hearings and workshops. Additional research has now demonstrated the carcinogenicity of VC to other organs and at lower concentrations. 5, pp. Vinyl chloride is used primarily to make polyvinyl chloride (PVC); PVC is used to make a variety of plastic products, including pipes, wire and cable coatings, and packaging materials. (4) • The vapor pressure for vinyl chloride is 2,600 mm Hg at 25 °C, and it has a log Vinyl chloride, a colourless, flammable, toxic gas belonging to the family of organohalogen compounds and used principally in making polyvinyl chloride, or PVC, a widely used plastic with numerous applications. Healthy Child Healthy World describes PVC as the most toxic plastic , and vinyl chloride, the chemical used to make PVC, has been described as a known carcinogen by the World Health Organization's International Agency for Research on Cancer. Case Studies in Environmental Medicine. Vinyl tile flooring is constructed of new or recycled polyvinyl chloride or PVC that is known to be one of the most environmentally hazardous consumer materials that are produced for flooring. 394-398. Vinyl chloride is a colorless gas that burns easily. The good news is that linoleum flooring looks and feels much like vinyl, but it’s an eco-friendly choice that is durable, biodegradable and made with natural materials such as linseed oil, limestone, tree resins, natural pigments, wood flour and jute. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of vinyl chloride. Short-term exposure to moderate levels of vinyl chloride in the air can result in a headache, vertigo, loss of consciousness, and fatigue.Nervous system damage is also possible. Notices. Vinyl chloride is an organochloride, flammable gas with a sickly sweet odor, which is a colorless at ambient temperature. Polyvinyl Chloride (PVC or Vinyl) is an economical and versatile thermoplastic polymer widely used in building and construction industry to produce door and window profiles, pipes (drinking and wastewater), wire and cable insulation, medical devices, etc. Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. * This data for Bis(2-ethylhexyl)Phthalate and Vinyl Chloride Monomer apply to the pure form of the compound. Doctors pinpointed the carcinogenicity of vinyl chloride in the late 1960s. QVC MSDS CODE : V3.0.2-1 MATERIAL SAFETY DATA SHEET – MSDS Product: VINYL CHLORIDE MONOMER Page 2 of 8 SDS No. Most often used in construction, PVC is a plastic composed of three elements: carbon, hydrogen and chlorine. Chloride Toxicity. : 003 Version : 05 Date : 12-10-2017 Prevention: Do not handle until all safety precautions have been read and understood. In Section 6, EPA has characterized its overall confidence in the quantitative and qualitative aspects of hazard and dose response. Some LVT manufacturers are committed to reducing the amount of PVC and phthalates, but many companies have not eliminated them. The Safe Drinking Water and Toxic Enforcement Act. PVC comes in two basic forms: rigid (sometimes abbreviated as RPVC) and flexible. Vinyl chloride has been classified as a human carcinogen (14th Report on Carcinogens, National Toxicity Program) and is on the Living Building Challenge Red List of toxic chemicals to avoid. From 1987 to 1993, according to EPA's Toxic Release Inventory, vinyl chloride releases to water and land totalled over 38,000 lbs. Vinyl Chloride Toxicity. American Industrial Hygiene Association Journal: Vol. • Vinyl chloride is a colorless, flammable gas with a mild, sweet odor. Polyvinyl chloride (PVC or vinyl) is the most toxic plastic for our health and the environment. 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